Characterization and Therapeutic Potential of Bacteriophage-Encoded Polysaccharide Depolymerases with β Galactosidase Activity against <i>Klebsiella pneumoniae</i> K57 Capsular Type

Characterization and Therapeutic Potential of Bacteriophage-Encoded Polysaccharide Depolymerases with β Galactosidase Activity against <i>Klebsiella pneumoniae</i> K57 Capsular Type

Bacteriophages and phage enzymes are considered as possible alternatives to antibiotics in the treatment of infections caused by antibiotic-resistant bacteria. Due to the ability to cleave the capsular polysaccharides (CPS), one of the main virulence factors of <i>Klebsiella pneumoniae</i&g...

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Bibliographic Details
Main Authors: Nikolay V. Volozhantsev, Anna M. Shpirt, Alexander I. Borzilov, Ekaterina V. Komisarova, Valentina M. Krasilnikova, Alexander S. Shashkov, Vladimir V. Verevkin, Yuriy A. Knirel
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Antibiotics
Subjects:
bacteriophage
polysaccharide depolymerase
<i>Klebsiella pneumoniae</i>
antimicrobial therapy
Online Access:https://www.mdpi.com/2079-6382/9/11/732

Internet

https://www.mdpi.com/2079-6382/9/11/732

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