B7-H4 Induces Donor-Specific Tolerance in Mouse Islet Allografts

B7-H4 Induces Donor-Specific Tolerance in Mouse Islet Allografts

Negative cosignaling molecules play an important role in regulating T-cell responses to alloantigen stimulation. We recently reported that adenoviral-mediated transduction of islet allografts with B7-H4 inhibits allograft rejection. In this study, we investigate the mechanism for B7-H4-induced prolo...

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Bibliographic Details
Main Authors: Xiaojie Wang, Jianqiang Hao, Daniel L. Metzger, Alice Mui, Ziliang Ao, C. Bruce Verchere, Lieping Chen, Dawei Ou, Garth L. Warnock M.D.
Format: Article
Language:English
Published: SAGE Publishing 2012-02-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X582750

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https://doi.org/10.3727/096368911X582750

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