Chronic RNA G-quadruplex accumulation in aging and Alzheimer’s disease

Chronic RNA G-quadruplex accumulation in aging and Alzheimer’s disease

As the world population ages, new molecular targets in aging and Alzheimer’s disease (AD) are needed to combat the expected influx of new AD cases. Until now, the role of RNA structure in aging and neurodegeneration has largely remained unexplored. In this study, we examined human hippocampal postmo...

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Bibliographic Details
Main Authors: Lena Kallweit, Eric Daniel Hamlett, Hannah Saternos, Anah Gilmore, Ann-Charlotte Granholm, Scott Horowitz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-02-01
Series:eLife
Subjects:
quadruplex
alzheimer's
aging
RNA
Tau
APOE
Online Access:https://elifesciences.org/articles/105446

Internet

https://elifesciences.org/articles/105446

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