Different activation of MAPKs and Akt/GSK3β after preload vs. afterload elevation

Different activation of MAPKs and Akt/GSK3β after preload vs. afterload elevation

Abstract Aims Pressure overload (PO) and volume overload (VO) lead to concentric or eccentric hypertrophy. Previously, we could show that activation of signalling cascades differ in in vivo mouse models. Activation of these signal cascades could either be induced by intrinsic load sensing or neuro‐e...

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Bibliographic Details
Main Authors: Nico Hartmann, Lena Preuß, Belal A. Mohamed, Moritz Schnelle, Andre Renner, Gerd Hasenfuß, Karl Toischer
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:ESC Heart Failure
Subjects:
Hypertrophy
Preload
Afterload
AKT‐GSK3β
MAPKs
Online Access:https://doi.org/10.1002/ehf2.13877

Internet

https://doi.org/10.1002/ehf2.13877

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