Effects of benidipine, paracetamol, and their combination on postoperative and normal tissue pain thresholds

Effects of benidipine, paracetamol, and their combination on postoperative and normal tissue pain thresholds

Introduction: In clinical practice, inadequate pain inhibition leads to increased morbidity and mortality. Increased intracellular calcium, oxidants, and proinflammatory cytokines are known to play a role in the pathogenesis of postoperative pain. Therefore, we investigated the analgesic effects of...

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Bibliographic Details
Main Authors: Zehra Bedir, Kezban Tuna Ozkaloglu Erdem, Omer Doymus, Halis Suleyman, Bulent Yavuzer, Betul Cicek, Durdu Altuner, Renad Mammadov, Mehmet Yilmaz, Taha Abdulkadir Coban, Bahadir Suleyman, Seval Bulut
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
benidipine
paracetamol
pain
rat
analgesic effect
proinflammatory cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1326128/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1326128/full

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