Properties of cell death models calibrated and compared using Bayesian approaches

Properties of cell death models calibrated and compared using Bayesian approaches

Abstract Using models to simulate and analyze biological networks requires principled approaches to parameter estimation and model discrimination. We use Bayesian and Monte Carlo methods to recover the full probability distributions of free parameters (initial protein concentrations and rate constan...

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Bibliographic Details
Main Authors: Hoda Eydgahi, William W Chen, Jeremy L Muhlich, Dennis Vitkup, John N Tsitsiklis, Peter K Sorger
Format: Article
Language:English
Published: Springer Nature 2013-02-01
Series:Molecular Systems Biology
Subjects:
apoptosis
Bayesian estimation
biochemical networks
modeling
Online Access:https://doi.org/10.1038/msb.2012.69

Internet

https://doi.org/10.1038/msb.2012.69

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