Macrophage-derived exosomes mediate glomerular endothelial cell dysfunction in sepsis-associated acute kidney injury
Abstract Background Sepsis-associated AKI has been shown to be related to sepsis mortality. Macrophage activation and endothelial cell damage are involved in the progression of sepsis-associated AKI, but the specific mechanisms are still unclear. Methods In vitro experiments, exosomes extracted from...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | Cell & Bioscience |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13578-023-00990-z |