Advances in CD30- and PD-1-targeted therapies for classical Hodgkin lymphoma

Abstract CD30 and programmed cell death protein 1 (PD-1) are two ideal therapeutic targets in classical Hodgkin lymphoma (cHL). The CD30 antibody-drug conjugate (ADC) brentuximab vedotin and the PD-1 antibodies nivolumab and pembrolizumab are highly efficacious in treating relapsed and/or refractory...

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Bibliographic Details
Main Authors: Yucai Wang, Grzegorz S. Nowakowski, Michael L. Wang, Stephen M. Ansell
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Hematology & Oncology
Online Access:http://link.springer.com/article/10.1186/s13045-018-0601-9