RKIP: A Key Regulator in Tumor Metastasis Initiation and Resistance to Apoptosis: Therapeutic Targeting and Impact

RAF-kinase inhibitor protein (RKIP) is a well-established tumor suppressor that is frequently downregulated in a plethora of solid and hematological malignancies. RKIP exerts antimetastatic and pro-apoptotic properties in cancer cells, via modulation of signaling pathways and gene products involved...

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Bibliographic Details
Main Authors: Apostolos Zaravinos, Benjamin Bonavida, Ekaterini Chatzaki, Stavroula Baritaki
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/9/287