Selective Continuous Positive Airway Pressure Withdrawal With Supplemental Oxygen During Slow-Wave Sleep as a Method of Dissociating Sleep Fragmentation and Intermittent Hypoxemia-Related Sleep Disruption in Obstructive Sleep Apnea

Selective Continuous Positive Airway Pressure Withdrawal With Supplemental Oxygen During Slow-Wave Sleep as a Method of Dissociating Sleep Fragmentation and Intermittent Hypoxemia-Related Sleep Disruption in Obstructive Sleep Apnea

Obstructive sleep apnea (OSA) is considered to impair memory processing and increase the expression of amyloid-β (Aβ) and risk for Alzheimer’s disease (AD). Given the evidence that slow-wave sleep (SWS) is important in both memory and Aβ metabolism, a better understanding of the mechanisms by which...

Full description

Bibliographic Details
Main Authors: Anna E. Mullins, Ankit Parekh, Korey Kam, Bresne Castillo, Zachary J. Roberts, Ahmad Fakhoury, Daphne I. Valencia, Reagan Schoenholz, Thomas M. Tolbert, Jason Z. Bronstein, Anne M. Mooney, Omar E. Burschtin, David M. Rapoport, Indu Ayappa, Andrew W. Varga
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Physiology
Subjects:
obstructive sleep apnea (OSA)
sleep disordered breathing
hypoxic burden
sleep disruption
arousal
desaturation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.750516/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.750516/full

Similar Items