Mode of Antibacterial Action of Tomatidine C3-Diastereoisomers

Mode of Antibacterial Action of Tomatidine C3-Diastereoisomers

Tomatidine (TO) is a natural narrow-spectrum antibiotic acting on the <i>Staphylococcus aureus</i> small colony variant (SCV) with a minimal inhibitory concentration (MIC) of 0.06 µg/mL while it shows no activity against prototypical strains (MIC > 128 µg/mL). To expand the spectrum o...

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Bibliographic Details
Main Authors: Jean-Philippe Langlois, Audrey Larose, Eric Brouillette, Julien A. Delbrouck, Pierre-Luc Boudreault, François Malouin
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
<i>Staphylococcus aureus</i>
<i>Escherichia coli</i>
ATP synthase inhibitor
tomatidine
antibiotic mode of action
bactericidal activity
Online Access:https://www.mdpi.com/1420-3049/29/2/343

Internet

https://www.mdpi.com/1420-3049/29/2/343

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