Glucose increases interleukin-12 gene expression and production in stimulated peripheral blood mononuclear cells of type 2 diabetes patients

Glucose increases interleukin-12 gene expression and production in stimulated peripheral blood mononuclear cells of type 2 diabetes patients

Background: Lipopolysaccharide (LPS)-stimulated peripheral blood mononuclear cells (PBMCs) of type 2 diabetes patients produce more interleukin (IL)-12 under glucose treatment. The aim of this study was to determine whether increased IL-12 response in hyperglycemic LPS-stimulated PBMCs is due to inc...

Full description

Bibliographic Details
Main Authors: Chien-Ming Chu, Sheng-Fong Kuo, Chung-Ching Hua, Shao-Yun Wu, Duen-Yau Chuang, Huang-Pin Wu
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Biomedical Journal
Subjects:
hyperglycemia
interleukin-12
osmolarity
peripheral blood mononuclear cells
sepsis
Online Access:http://www.biomedj.org/article.asp?issn=2319-4170;year=2014;volume=37;issue=5;spage=293;epage=297;aulast=Chu

Internet

http://www.biomedj.org/article.asp?issn=2319-4170;year=2014;volume=37;issue=5;spage=293;epage=297;aulast=Chu

Similar Items