Consequences of the Lack of TNFR1 in Ouabain Response in the Hippocampus of C57BL/6J Mice

Ouabain is a cardiac glycoside that has a protective effect against neuroinflammation at low doses through Na<sup>+</sup>/K<sup>+</sup>-ATPase signaling and that can activate tumor necrosis factor (TNF) in the brain. TNF plays an essential role in neuroinflammation and regula...

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Bibliographic Details
Main Authors: Paula Fernanda Kinoshita, Ana Maria Orellana, Diana Zukas Andreotti, Giovanna Araujo de Souza, Natalia Prudente de Mello, Larissa de Sá Lima, Elisa Mitiko Kawamoto, Cristoforo Scavone
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/11/2937