The IGR-CaP1 Xenograft Model Recapitulates Mixed Osteolytic/Blastic Bone Lesions Observed in Metastatic Prostate Cancer

Bone metastases have a devastating impact on quality of life and bone pain in patients with prostate cancer and decrease survival. Animal models are important tools in investigating the pathogenesis of the disease and in developing treatment strategies for bone metastases, but few animal models reca...

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Bibliographic Details
Main Authors: Nader Al Nakouzi, Olivia Bawa, Alain Le Pape, Stéphanie Lerondel, Catherine Gaudin, Paule Opolon, Patrick Gonin, Karim Fizazi, Anne Chauchereau
Format: Article
Language:English
Published: Elsevier 2012-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800133