Cellular Gene Expression during Hepatitis C Virus Replication as Revealed by Ribosome Profiling

Cellular Gene Expression during Hepatitis C Virus Replication as Revealed by Ribosome Profiling

Background: Hepatitis C virus (HCV) infects human liver hepatocytes, often leading to liver cirrhosis and hepatocellular carcinoma (HCC). It is believed that chronic infection alters host gene expression and favors HCC development. In particular, HCV replication in Endoplasmic Reticulum (ER) derived...

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Bibliographic Details
Main Authors: Gesche K. Gerresheim, Jochen Bathke, Audrey M. Michel, Dmitri E. Andreev, Lyudmila A. Shalamova, Oliver Rossbach, Pan Hu, Dieter Glebe, Markus Fricke, Manja Marz, Alexander Goesmann, Stephen J. Kiniry, Pavel V. Baranov, Ivan N. Shatsky, Michael Niepmann
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
HCV
HCC
hepatocellular carcinoma
liver cancer
Warburg effect
ER stress
ribosome profiling
Riboseq
respiratory chain
mitochondria
Online Access:http://www.mdpi.com/1422-0067/20/6/1321

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http://www.mdpi.com/1422-0067/20/6/1321

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