Advances in sequencing technologies for amyotrophic lateral sclerosis research

Advances in sequencing technologies for amyotrophic lateral sclerosis research

Abstract Amyotrophic lateral sclerosis (ALS) is caused by upper and lower motor neuron loss and has a fairly rapid disease progression, leading to fatality in an average of 2-5 years after symptom onset. Numerous genes have been implicated in this disease; however, many cases remain unexplained. Sev...

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Bibliographic Details
Main Authors: Evan Udine, Angita Jain, Marka van Blitterswijk
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Molecular Neurodegeneration
Subjects:
Amyotrophic lateral sclerosis
DNA sequencing
Long-read sequencing
SMRT sequencing
Nanopore sequencing
Multi-omics
Online Access:https://doi.org/10.1186/s13024-022-00593-1

Internet

https://doi.org/10.1186/s13024-022-00593-1

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