Computational investigation of the changing patterns of subtype specific NMDA receptor activation during physiological glutamatergic neurotransmission.

NMDA receptors (NMDARs) are the major mediator of the postsynaptic response during synaptic neurotransmission. The diversity of roles for NMDARs in influencing synaptic plasticity and neuronal survival is often linked to selective activation of multiple NMDAR subtypes (NR1/NR2A-NMDARs, NR1/NR2B-NMDA...

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Bibliographic Details
Main Authors: Pallab Singh, Adam J Hockenberry, Vineet R Tiruvadi, David F Meaney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3127809?pdf=render