Synthesis of Bistetrahydroquinolines as Potential Anticholinesterasic Agents by Double Diels-Alder Reactions

The tetrahydroquinoline ring system is a unit found in many biologically active natural products and pharmacologically relevant therapeutic agents. A new series of bistetrahydroquinolines (bis-THQs) was synthesized using imino Diels-Alder reactions between dialdehydes, anilines and N-vinyl-2-pyrroli...

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Bibliographic Details
Main Authors: Natalia Valdés, Jans Alzate-Morales, Luis Astudillo, Yorley Duarte, Margarita Gutiérrez
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/10/12951