A pH‐responsive nanoparticle delivery system containing dihydralazine and doxorubicin‐based prodrug for enhancing antitumor efficacy

A pH‐responsive nanoparticle delivery system containing dihydralazine and doxorubicin‐based prodrug for enhancing antitumor efficacy

Abstract The efficacy of nanoparticle (NP)‐based drug delivery technology is hampered by aberrant tumor stromal microenvironments (TSMs) that hinder NP transportation. Therefore, the promotion of NP permeation into deep tumor sites via the regulation of tumor microenvironments is of critical importa...

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Bibliographic Details
Main Authors: Lianxue Zhang, Jianxiang Huang, Damiano Buratto, Panli Han, Zaixing Yang, Ruhong Zhou
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Aggregate
Subjects:
antitumor
dihydralazine
drug delivery system
tumor stromal microenvironment
vasculature
Online Access:https://doi.org/10.1002/agt2.434

Internet

https://doi.org/10.1002/agt2.434

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