Total Synthesis and Anti-HIV Activity Evaluation of Desmosdumotin D and Analogues

Total Synthesis and Anti-HIV Activity Evaluation of Desmosdumotin D and Analogues

The natural product Desmosdumotin D (hereafter referred to as <b>Des-D</b>), isolated from the plant <i>Desmos dumosus</i>, showed potent anti-HIV activity. However, the subsequent pharmacological activity and clinical studies are limited due to the low content of <b>De...

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Bibliographic Details
Main Authors: Ying Deng, Xiaoping Song, Tongtong Yun, Zuo Xiang, Guanghui Wang, Gang Li, Yanxin Zhang, Yiming Song, Qingchao Liu
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Drugs and Drug Candidates
Subjects:
Desmosdumotin D
chemical synthesis
analogue
HIV-1
Online Access:https://www.mdpi.com/2813-2998/3/1/3

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https://www.mdpi.com/2813-2998/3/1/3

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