Lactic acid modified rare earth-based nanomaterials for enhanced radiation therapy by disturbing the glycolysis
Abstract Deficient deposition of X-rays and strong capacity of repairing damage DNA of cancer cells limit the effect of radiation therapy (RT). Herein, we synthesize CsLu2F7 nanoparticles with lactic acid (LA) ligands (CsLu2F7-LA) to overcome these limitations. The high-Z atoms of Lu and Cs can depo...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-11-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12951-022-01694-1 |