Lactic acid modified rare earth-based nanomaterials for enhanced radiation therapy by disturbing the glycolysis

Lactic acid modified rare earth-based nanomaterials for enhanced radiation therapy by disturbing the glycolysis

Abstract Deficient deposition of X-rays and strong capacity of repairing damage DNA of cancer cells limit the effect of radiation therapy (RT). Herein, we synthesize CsLu2F7 nanoparticles with lactic acid (LA) ligands (CsLu2F7-LA) to overcome these limitations. The high-Z atoms of Lu and Cs can depo...

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Bibliographic Details
Main Authors: Hu Liu, Han Wang, Dalong Ni, Youjia Xu
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Journal of Nanobiotechnology
Subjects:
Nanomedicine
Rare earth
Radiation therapy
Lactic acid
Glycolysis
Online Access:https://doi.org/10.1186/s12951-022-01694-1

Internet

https://doi.org/10.1186/s12951-022-01694-1

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