Anticancer effect of zoledronic acid in endocrine-resistant breast cancer cells via HER-2 signaling

Anticancer effect of zoledronic acid in endocrine-resistant breast cancer cells via HER-2 signaling

HER-2 overexpression is a major mechanism involved in endocrine-resistant breast cancer, which has very limited treatment options. Zoledronic acid (ZA) is a drug in the bisphosphonate group used to treat osteoporosis. ZA was reported to exhibit activity in various cancers, with higher efficacy assoc...

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Bibliographic Details
Main Authors: Patthamapon Adchariyasakulchai, Nithidol Sakunrangsit, Sarun Chokyakorn, Chayanin Suksanong, Wannarasmi Ketchart
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
AKT
Breast cancer
Endocrine resistance, ERK
HER-2
Zoledronic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224000234

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http://www.sciencedirect.com/science/article/pii/S0753332224000234

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