Bacterial Genotoxin-Induced DNA Damage and Modulation of the Host Immune Microenvironment

Bacterial genotoxins (BTGX) induce DNA damage, which results in senescence or apoptosis of the target cells if not properly repaired. Three BTGXs have been identified: the cytolethal distending toxin (CDT) family produced by several Gram-negative bacteria, the typhoid toxin produced by several <i...

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Bibliographic Details
Main Authors: Océane C.B. Martin, Teresa Frisan
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/2/63