Inflammation and immunomodulatory therapies influence the relationship between ATP-binding cassette A1 membrane transporter-mediated cholesterol efflux capacity and coronary atherosclerosis in rheumatoid arthritis

Inflammation and immunomodulatory therapies influence the relationship between ATP-binding cassette A1 membrane transporter-mediated cholesterol efflux capacity and coronary atherosclerosis in rheumatoid arthritis

Objectives: High-density lipoprotein (HDL) removes cholesterol from cells in atherosclerotic lesions, a function known as cholesterol efflux capacity (CEC). ATP-binding-cassette A1 (ABCA1) membrane transporter starts cholesterol transfer from macrophages to HDL particles. In rheumatoid arthritis (RA...

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Bibliographic Details
Main Authors: George A. Karpouzas, Bianca Papotti, Sarah R. Ormseth, Marcella Palumbo, Elizabeth Hernandez, Maria Pia Adorni, Francesca Zimetti, Matthew J. Budoff, Nicoletta Ronda
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Translational Autoimmunity
Subjects:
Rheumatoid arthritis
Coronary atherosclerosis
Cardiovascular events
Cholesterol efflux capacity
ABCA1
Corticosteroids
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909023000229

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http://www.sciencedirect.com/science/article/pii/S2589909023000229

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