Influence of Glucose on <i>Candida albicans</i> and the Relevance of the Complement FH-Binding Molecule Hgt1 in a Murine Model of Candidiasis

Influence of Glucose on <i>Candida albicans</i> and the Relevance of the Complement FH-Binding Molecule Hgt1 in a Murine Model of Candidiasis

Candidiasis is common in diabetic patients. Complement evasion is facilitated by binding complement factor H (FH). Since the expression of high-affinity glucose transporter 1 (Hgt1), a FH-binding molecule, is glucose-dependent, we aimed to study its relevance to the pathogenesis of <i>Candida...

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Bibliographic Details
Main Authors: Verena Harpf, Samyr Kenno, Günter Rambach, Verena Fleischer, Nadia Parth, Christian X. Weichenberger, Peter Garred, Silke Huber, Cornelia Lass-Flörl, Cornelia Speth, Reinhard Würzner
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Antibiotics
Subjects:
<i>Candida albicans</i>
Hgt1
diabetes
complement
factor H
C3
Online Access:https://www.mdpi.com/2079-6382/11/2/257

Internet

https://www.mdpi.com/2079-6382/11/2/257

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