Corilagin enhances the anti-tumor activity of 5-FU by downregulating the expression of GRP 78

Abstract Colorectal cancer is one of the most common malignancies worldwide. Although initially effective, patients who receive chemotherapy ultimately experience various complications and develop chemo-resistance, leading to cancer recurrence. Therefore, we aimed to find a drug with good efficacy a...

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Bibliographic Details
Main Authors: Simin Li, Xinquan Li, Xiliang Yang, Yumeng Lei, Mingxin He, Xiaochen Xiang, Qingming Wu, Hongyun Liu, Jiadun Wang, Qiang Wang
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49604-1