HLA-DQA1*05 Associates with Extensive Ulcerative Colitis at Diagnosis: An Observational Study in Children

HLA-DQA1*05 Associates with Extensive Ulcerative Colitis at Diagnosis: An Observational Study in Children

The human leukocyte antigen (HLA) allele group HLA-DQA1*05 predisposes to ulcerative colitis (UC) and is associated with the development of antibodies against infliximab in patients with inflammatory bowel disease (IBD). Therefore, we hypothesized that the presence of HLA-DQA1*05 correlates with cha...

Full description

Bibliographic Details
Main Authors: Jan Krzysztof Nowak, Aleksandra Glapa-Nowak, Aleksandra Banaszkiewicz, Barbara Iwańczak, Jarosław Kwiecień, Anna Szaflarska-Popławska, Urszula Grzybowska-Chlebowczyk, Marcin Osiecki, Jarosław Kierkuś, Magdalena Hołubiec, Justyna Chanaj-Kaczmarek, Andrzej Radzikowski, Jarosław Walkowiak
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Genes
Subjects:
inflammatory bowel disease
colitis
Crohn’s disease
anti-drug antibodies
personalized medicine
high-resolution melting
Online Access:https://www.mdpi.com/2073-4425/12/12/1934

Internet

https://www.mdpi.com/2073-4425/12/12/1934

Similar Items