Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor

Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor

Abstract Cannabidiol (CBD), the major non-psychotomimetic compound present in the Cannabis sativa plant, exhibits therapeutic potential for various human diseases, including chronic neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, ischemic stroke, epilepsy and other convulsive syndro...

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Bibliographic Details
Main Authors: María Rodríguez-Muñoz, Yara Onetti, Elsa Cortés-Montero, Javier Garzón, Pilar Sánchez-Blázquez
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Molecular Brain
Subjects:
Cannabidiol
Cannabinoids
Sigma 1 receptor
NMDA receptor
Neuropathology
Epilepsy
Online Access:http://link.springer.com/article/10.1186/s13041-018-0395-2

Internet

http://link.springer.com/article/10.1186/s13041-018-0395-2

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