Synthesis and Evaluation of Novel <i>S</i>-alkyl Phthalimide- and <i>S</i>-benzyl-oxadiazole-quinoline Hybrids as Inhibitors of Monoamine Oxidase and Acetylcholinesterase

Synthesis and Evaluation of Novel <i>S</i>-alkyl Phthalimide- and <i>S</i>-benzyl-oxadiazole-quinoline Hybrids as Inhibitors of Monoamine Oxidase and Acetylcholinesterase

New <i>S</i>-alkyl phthalimide <b>5a</b>–<b>f</b> and <i>S</i>-benzyl <b>6a</b>–<b>d</b> analogs of 5-(2-phenylquinolin-4-yl)-1,3,4-oxadiazole-2-thiol (<b>4</b>) were prepared by reacting <b>4</b> with &l...

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Bibliographic Details
Main Authors: Bilal Ahmad Khan, Syeda Shamila Hamdani, Saquib Jalil, Syeda Abida Ejaz, Jamshed Iqbal, Ahmed M. Shawky, Alaa M. Alqahtani, Gamal A. Gabr, Mahmoud A. A. Ibrahim, Peter A. Sidhom
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceuticals
Subjects:
oxadiazole-quinoline hybrids
Alzheimer’s illness
monoamine oxidase
AChE
molecular modeling
Online Access:https://www.mdpi.com/1424-8247/16/1/11

Internet

https://www.mdpi.com/1424-8247/16/1/11

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