Modeling the SDF-1/CXCR4 protein using advanced artificial intelligence and antagonist screening for Japanese anchovy

Modeling the SDF-1/CXCR4 protein using advanced artificial intelligence and antagonist screening for Japanese anchovy

SDF-1/CXCR4 chemokine signaling are indispensable for cell migration, especially the Primordial Germ Cell (PGC) migration towards the gonadal ridge during early development. We earlier found that this signaling is largely conserved in the Japanese anchovy (Engraulis japonicus, EJ), and a mere treatm...

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Bibliographic Details
Main Authors: Issei Yahiro, Kyle Dominic Eguid Barnuevo, Oga Sato, Sipra Mohapatra, Atsushi Toyoda, Takehiko Itoh, Kaoru Ohno, Michiya Matsuyama, Tapas Chakraborty, Kohei Ohta
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Physiology
Subjects:
SDF-1/CXCR4
Colab Fold
CB Dock
Alpha Fold
PGC
Japanese anchovy
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1349119/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2024.1349119/full

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