Therapeutic Implications of TGF-β Pathway in Desmoid Tumor Based on Comprehensive Molecular Profiling and Clinicopathological Properties

Therapeutic Implications of TGF-β Pathway in Desmoid Tumor Based on Comprehensive Molecular Profiling and Clinicopathological Properties

(1) Background: Desmoid tumors have a relatively high local failure rate after primary treatment using surgery and/or radiotherapy. Moreover, desmoid tumors recur at the primary site for many patients. An effective therapeutic strategy for the desmoid tumor is needed to maintain quality of life and...

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Bibliographic Details
Main Authors: Kum-Hee Yun, Changhee Park, Hyang Joo Ryu, Chan-Young Ock, Young Han Lee, Wooyeol Baek, Hong In Yoon, Yoon Dae Han, Sang Kyum Kim, JooHee Lee, Seong-Jin Kim, Kyung-Min Yang, Seung Hyun Kim, Hyo Song Kim
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
desmoid tumor
rare cancer
next-generation sequencing
TGF-β pathway
combination treatment
patient-derived primary cell model
Online Access:https://www.mdpi.com/2072-6694/14/23/5975

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https://www.mdpi.com/2072-6694/14/23/5975

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