Over-expression of miR-106b promotes cell migration and metastasis in hepatocellular carcinoma by activating epithelial-mesenchymal transition process.

Hepatocellular carcinoma (HCC) is one the the most fatal cancers worldwide. The poor prognosis of HCC is mainly due to the developement of distance metastasis. To investigate the mechanism of metastasis in HCC, an orthotopic HCC metastasis animal model was established. Two sets of primary liver tumo...

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Bibliographic Details
Main Authors: Wing Lung Yau, Colin Siu Chi Lam, Lui Ng, Ariel Ka Man Chow, Sylvia Tsz Ching Chan, Jacky Yu Ki Chan, Jana Yim Hung Wo, Kevin Tak Pan Ng, Kwan Man, Ronnie Tung Ping Poon, Roberta Wen Chi Pang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590302?pdf=render