Structural interplay of anesthetics and paralytics on muscle nicotinic receptors

Abstract General anesthetics and neuromuscular blockers are used together during surgery to stabilize patients in an unconscious state. Anesthetics act mainly by potentiating inhibitory ion channels and inhibiting excitatory ion channels, with the net effect of dampening nervous system excitability....

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Bibliographic Details
Main Authors: Umang Goswami, Md Mahfuzur Rahman, Jinfeng Teng, Ryan E. Hibbs
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38827-5