Differential regulation of Shigella Spa47 ATPase activity by a native C-terminal product of Spa33

Shigella is a Gram-negative bacterial pathogen that relies on a single type three secretion system (T3SS) as its primary virulence factor. The T3SS includes a highly conserved needle-like apparatus that directly injects bacterial effector proteins into host cells, subverting host cell function, init...

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Bibliographic Details
Main Authors: Heather B. Case, Saul Gonzalez, Marie E. Gustafson, Nicholas E. Dickenson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1183211/full