Nobiletin Stimulates Chloride Secretion in Human Bronchial Epithelia via a cAMP/PKA-Dependent Pathway

Nobiletin Stimulates Chloride Secretion in Human Bronchial Epithelia via a cAMP/PKA-Dependent Pathway

Background/Aims: Nobiletin, a citrus flavonoid isolated from tangerines, alters ion transport functions in intestinal epithelia, and has antagonistic effects on eosinophilic airway inflammation of asthmatic rats. The present study examined the effects of nobiletin on basal short-circuit current (ISC...

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Bibliographic Details
Main Authors: Yuan Hao, Cindy S.T. Cheung, Wallace C.Y. Yip, Wing-hung Ko
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Flavonoid
Nobiletin
Chloride secretion
cAMP/PKA
Bronchial epithelia
Online Access:http://www.karger.com/Article/FullText/430355

Internet

http://www.karger.com/Article/FullText/430355

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