APC protein immunoexpression in colorectal adenoma and adenocarcinoma

Background: activation of the Wnt pathway by mutated APC gene is considered the initial event in colorectal carcinogenesis. The identification of these mutations can improve the specific treatment of the adenocarcinoma. Objective: detect and evaluate wild-type APC protein in tissue from colorectal a...

Full description

Bibliographic Details
Main Authors: Vivian Sati Oba Bourroul, Guilherme Muniz Bourroul, Giovanna Canato Toloi, Rogério Tadeu Palma, Celina Tizuko Fujiyama Oshima, Thiago Simão Gomes, Sílvia Saiuli Miki Ihara, Jaques Waisberg
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2013-07-01
Series:Journal of Coloproctology
Online Access:http://www.sciencedirect.com/science/article/pii/S2237936313000373