APC protein immunoexpression in colorectal adenoma and adenocarcinoma
Background: activation of the Wnt pathway by mutated APC gene is considered the initial event in colorectal carcinogenesis. The identification of these mutations can improve the specific treatment of the adenocarcinoma. Objective: detect and evaluate wild-type APC protein in tissue from colorectal a...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Thieme Revinter Publicações Ltda.
2013-07-01
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Series: | Journal of Coloproctology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2237936313000373 |