Effect of Trichostatin A on Histone Deacetylases 1, 2 and 3, p21Cip1/Waf1/Sdi1, p27Kip1, and p57Kip2 Gene Expression in Breast Cancer SK-BR-3 Cell Line

Objective: DNA methylation, the covalent addition of a methyl group to cytosine, and histone modification play an important role in the establishment and maintenance of the program of gene expression. The balance of histone acetylation is determined by the activities of two groups of enzymes includi...

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Bibliographic Details
Main Authors: Masumeh Sanaei, Fraidoon Kavoosi
Format: Article
Language:English
Published: West Asia Organization for Cancer Prevention 2020-06-01
Series:Asian Pacific Journal of Cancer Biology
Subjects:
Online Access:http://www.waocp.com/journal/index.php/apjcb/article/view/396