Effect of Trichostatin A on Histone Deacetylases 1, 2 and 3, p21Cip1/Waf1/Sdi1, p27Kip1, and p57Kip2 Gene Expression in Breast Cancer SK-BR-3 Cell Line
Objective: DNA methylation, the covalent addition of a methyl group to cytosine, and histone modification play an important role in the establishment and maintenance of the program of gene expression. The balance of histone acetylation is determined by the activities of two groups of enzymes includi...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
West Asia Organization for Cancer Prevention
2020-06-01
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Series: | Asian Pacific Journal of Cancer Biology |
Subjects: | |
Online Access: | http://www.waocp.com/journal/index.php/apjcb/article/view/396 |