Taxon Disappearance from Microbiome Analysis Reinforces the Value of Mock Communities as a Standard in Every Sequencing Run

Taxon Disappearance from Microbiome Analysis Reinforces the Value of Mock Communities as a Standard in Every Sequencing Run

ABSTRACT Mock communities have been used in microbiome method development to help estimate biases introduced in PCR amplification and sequencing and to optimize pipeline outputs. Nevertheless, the strong value of routine mock community analysis beyond initial method development is rarely, if ever, c...

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Bibliographic Details
Main Authors: Yi-Chun Yeh, David M. Needham, Ella T. Sieradzki, Jed A. Fuhrman
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mSystems
Subjects:
DNA sequencing
microbiome analysis
mock community
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00023-18

Internet

https://journals.asm.org/doi/10.1128/mSystems.00023-18

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