Postsynaptic structure formation of human iPS cell-derived neurons takes longer than presynaptic formation during neural differentiation in vitro

Postsynaptic structure formation of human iPS cell-derived neurons takes longer than presynaptic formation during neural differentiation in vitro

Abstract The generation of mature synaptic structures using neurons differentiated from human-induced pluripotent stem cells (hiPSC-neurons) is expected to be applied to physiological studies of synapses in human cells and to pathological studies of diseases that cause abnormal synaptic function. Al...

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Bibliographic Details
Main Authors: Kazuyuki Togo, Hayato Fukusumi, Tomoko Shofuda, Hiroshi Ohnishi, Hiroyuki Yamazaki, Mariko Kato Hayashi, Nana Kawasaki, Nobuyuki Takei, Takanobu Nakazawa, Yumiko Saito, Kousuke Baba, Hitoshi Hashimoto, Yuko Sekino, Tomoaki Shirao, Hideki Mochizuki, Yonehiro Kanemura
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Molecular Brain
Subjects:
Human-induced pluripotent stem cell
Neural progenitor cell
Vesicular glutamate transporter 2 (VGLUT2)
Drebrin
PSD-95
Online Access:https://doi.org/10.1186/s13041-021-00851-1

Internet

https://doi.org/10.1186/s13041-021-00851-1

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