The third model of Bax/Bak activation: a Bcl-2 family feud finally resolved? [version 1; peer review: 3 approved]

Bax and Bak, two functionally similar, pro-apoptotic proteins of the Bcl-2 family, are known as the gateway to apoptosis because of their requisite roles as effectors of mitochondrial outer membrane permeabilization (MOMP), a major step during mitochondria-dependent apoptosis. The mechanism of how c...

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Bibliographic Details
Main Authors: Xu Luo, Katelyn L. O'Neill, Kai Huang
Format: Article
Language:English
Published: F1000 Research Ltd 2020-08-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-935/v1