The third model of Bax/Bak activation: a Bcl-2 family feud finally resolved? [version 1; peer review: 3 approved]
Bax and Bak, two functionally similar, pro-apoptotic proteins of the Bcl-2 family, are known as the gateway to apoptosis because of their requisite roles as effectors of mitochondrial outer membrane permeabilization (MOMP), a major step during mitochondria-dependent apoptosis. The mechanism of how c...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2020-08-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/9-935/v1 |