Identification of Sortilin Alternatively Spliced Variants in Mouse 3T3L1 Adipocytes

Identification of Sortilin Alternatively Spliced Variants in Mouse 3T3L1 Adipocytes

Type 2 diabetes mellitus is a metabolic disorder defined by systemic insulin resistance. Insulin resistance in adipocytes, an important regulator of glucose metabolism, results in impaired glucose uptake. The trafficking protein, sortilin, regulates major glucose transporter 4 (Glut4) movement, ther...

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Bibliographic Details
Main Authors: Ashley Lui, Robert Sparks, Rekha Patel, Niketa A. Patel
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
Sortilin
Glut4
alternative splicing
adipocytes
molecular dynamics
protein–protein docking
Online Access:https://www.mdpi.com/1422-0067/22/3/983

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https://www.mdpi.com/1422-0067/22/3/983

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