Immunotherapy that improves response to chemotherapy in high-grade serous ovarian cancer

Immunotherapy that improves response to chemotherapy in high-grade serous ovarian cancer

Abstract Single-cell RNA sequencing (scRNAseq) of tumour-infiltrating immune cells in high-grade serous ovarian cancer (HGSOC) omental biopsies reveals potential targets that could enhance response to neo-adjuvant chemotherapy (NACT). Analysis of 64,097 cells identifies NACT-induced overexpression o...

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Bibliographic Details
Main Authors: Samar Elorbany, Chiara Berlato, Larissa S. Carnevalli, Eleni Maniati, Simon T. Barry, Jun Wang, Ranjit Manchanda, Julia Kzhyshkowska, Frances Balkwill
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54295-x

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https://doi.org/10.1038/s41467-024-54295-x

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