The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster.

The coordination of cell proliferation and differentiation is crucial for proper development. In particular, robust mechanisms exist to ensure that cells permanently exit the cell cycle upon terminal differentiation, and these include restraining the activities of both the E2F/DP transcription facto...

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Bibliographic Details
Main Authors: Jennifer L Bandura, Huaqi Jiang, Derek W Nickerson, Bruce A Edgar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3784567?pdf=render