Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method

Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method

Organ ischemia-reperfusion injury (IRI), which is unavoidable in kidney transplantation, induces the formation of reactive oxygen species and causes organ damage. Although the efficacy of molecular hydrogen (H2) in IRI has been reported, oral intake of H2-rich water and inhalation of H2 gas are stil...

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Bibliographic Details
Main Authors: Masataka Kawamura, Ryoichi Imamura, Yuki Kobayashi, Ayumu Taniguchi, Shigeaki Nakazawa, Taigo Kato, Tomoko Namba-Hamano, Toyofumi Abe, Motohide Uemura, Hikaru Kobayashi, Norio Nonomura
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Medicine
Subjects:
silicon
ischemia reperfusion injury
hydrogen
oxidative stress
kidney
rat
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00095/full

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https://www.frontiersin.org/article/10.3389/fmed.2020.00095/full

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