Exposure Route Influences Disease Severity in the COVID-19 Cynomolgus Macaque Model

Exposure Route Influences Disease Severity in the COVID-19 Cynomolgus Macaque Model

The emergence of SARS-CoV-2 and the subsequent pandemic has highlighted the need for animal models that faithfully replicate the salient features of COVID-19 disease in humans. These models are necessary for the rapid selection, testing, and evaluation of potential medical countermeasures. Here, we...

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Bibliographic Details
Main Authors: Sandra L. Bixler, Christopher P. Stefan, Alexandra N. Jay, Franco D. Rossi, Keersten M. Ricks, Charles J. Shoemaker, Alicia M. Moreau, Xiankun Zeng, Jay W. Hooper, David N. Dyer, Ondraya M. Frick, Jeffrey W. Koehler, Brian J. Kearney, Nina DiPinto, Jun Liu, Samantha D. Tostenson, Tamara L. Clements, Jeffrey M. Smith, Joshua A. Johnson, Kerry L. Berrier, Heather L. Esham, Korey L. Delp, Susan R. Coyne, Holly A. Bloomfield, Paul A. Kuehnert, Kristen Akers, Kathleen M. Gibson, Timothy D. Minogue, Aysegul Nalca, Margaret L. M. Pitt
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Viruses
Subjects:
SARS-CoV-2
COVID
nonhuman primate
aerosol
pathology
animal models
Online Access:https://www.mdpi.com/1999-4915/14/5/1013

Internet

https://www.mdpi.com/1999-4915/14/5/1013

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