Genome-wide association data reveal a global map of genetic interactions among protein complexes.

This work demonstrates how gene association studies can be analyzed to map a global landscape of genetic interactions among protein complexes and pathways. Despite the immense potential of gene association studies, they have been challenging to analyze because most traits are complex, involving the...

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Bibliographic Details
Main Authors: Gregory Hannum, Rohith Srivas, Aude Guénolé, Haico van Attikum, Nevan J Krogan, Richard M Karp, Trey Ideker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2788232?pdf=render