PTBP1 Regulates DNMT3B Alternative Splicing by Interacting With RALY to Enhance the Radioresistance of Prostate Cancer

PTBP1 Regulates DNMT3B Alternative Splicing by Interacting With RALY to Enhance the Radioresistance of Prostate Cancer

Abstract Radiotherapy is a curative arsenal for prostate cancer (PCa), but radioresistance seriously compromises its effectiveness. Dysregulated RNA splicing factors are extensively involved in tumor progression. Nonetheless, the role of splicing factors in radioresistance remains largely unexplored...

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Bibliographic Details
Main Authors: Haixia He, Qianghua Zhou, Yangjie Zhang, Yi Li, Lin Ding, Ting Shen, Sen Liu, Shengmeng Peng, Ming Huang, Hua Zhou, Liang Cheng, Ruihui Xie, Qiang Zhang, Junlin Lu, Liting Li, Jing Yang, Shoumin Bai, Tianxin Lin, Xu Chen
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
DNMT3B
prostate cancer
PTBP1
radioresistance
splicing factor
Online Access:https://doi.org/10.1002/advs.202405997

Internet

https://doi.org/10.1002/advs.202405997

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