Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres [version 1; referees: 2 approved]

Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres [version 1; referees: 2 approved]

Background: Although thousands of clinical isolates of Plasmodium falciparum are being sequenced and analysed by short read technology, the data do not resolve the highly variable subtelomeric regions of the genomes that contain polymorphic gene families involved in immune evasion and pathogenesis....

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Main Authors: Thomas D. Otto, Ulrike Böhme, Mandy Sanders, Adam Reid, Ellen I. Bruske, Craig W. Duffy, Pete C. Bull, Richard D. Pearson, Abdirahman Abdi, Sandra Dimonte, Lindsay B. Stewart, Susana Campino, Mihir Kekre, William L. Hamilton, Antoine Claessens, Sarah K. Volkman, Daouda Ndiaye, Alfred Amambua-Ngwa, Mahamadou Diakite, Rick M. Fairhurst, David J. Conway, Matthias Franck, Chris I. Newbold, Matt Berriman
Format: Article
Language:English
Published: Wellcome 2018-05-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-52/v1

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https://wellcomeopenresearch.org/articles/3-52/v1

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