Effect of combination fluoxetine and exercise on prefrontal BDNF, anxiety-like behavior and fear extinction in a female rat model of post-traumatic stress disorder (PTSD): a comparison with male animals

Abstract Despite significant differences between men and women in the symptoms of PTSD and the response to therapeutic interventions, most PTSD studies have been done on male subjects. Continuing our previous study in male rats, this study aimed at better understanding the effect of a combination th...

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Bibliographic Details
Main Authors: Sakineh Shafia, Farkhonde Nikkhah, Kobra Akhoundzadeh
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Behavioral and Brain Functions
Subjects:
Online Access:https://doi.org/10.1186/s12993-023-00204-z