High-throughput extraction on a dynamic solid phase for low-abundance biomarker isolation from biological samples

Abstract Liquid biopsy, in particular circulating tumor DNA (ctDNA) analysis, has paved the way for a new noninvasive approach to cancer diagnosis, treatment selection and follow-up. As a crucial step in the analysis, the extraction of the genetic material from a complex matrix needs to meet specifi...

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Bibliographic Details
Main Authors: Lucile Alexandre, Monica Araya-Farias, Manh-Louis Nguyen, Nikoletta Naoumi, Giacomo Gropplero, Electra Gizeli, Laurent Malaquin, Stéphanie Descroix
Format: Article
Language:English
Published: Nature Publishing Group 2023-09-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-023-00582-4